Kingdom.Rush.Origins-SiMPLEX Generator
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In patients with good outcome, but not in those with poor outcome, the seizure source tends to localize to the resection territory. The source is a dynamic entity that moves and evolves over the course of a seizure. Our approach also successfully localizes interictal spikes. Interictal spikes emerge from multiple distinct foci in each patient. Seizures either arise from or travel to interictal spike generators. Finally, both patterns of seizure spread and interictal spike networks respect white matter tracts. Only interictal spike foci which give rise to or receive seizures tend to be mutually connected via white matter tracts. 2b1af7f3a8